Design and Characterization of a Broad -Spectrum Bactericidal Acyl-lysyl Oligomer
نویسندگان
چکیده
منابع مشابه
Antibacterial properties and mode of action of a short acyl-lysyl oligomer.
We investigated the potency, selectivity, and mode of action of the oligo-acyl-lysine (OAK) NC(12)-2 beta(12), which was recently suggested to represent the shortest OAK sequence that retains nonhemolytic antibacterial properties. A growth inhibition assay against a panel of 48 bacterial strains confirmed that NC(12)-2 beta(12) exerted potent activity against gram-positive bacteria while exhibi...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2009
ISSN: 1074-5521
DOI: 10.1016/j.chembiol.2009.11.012